What are the chances of having a baby with sickle cell trait?

When ONE parent has sickle cell trait and the other parent has normal hemoglobin the child may inherit:

  • two normal hemoglobin genes, or
  • one normal hemoglobin gene and one sickle cell gene.

With EACH pregnancy there is a:

  • 50% chance that the baby will have normal red blood cells (AA).
  • 50% chance that the baby will have sickle cell trait (AS).
One parent with sickle cell trait

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