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Sickle cell trait occurs when a person inherits a normal hemoglobin gene (Hb A) from one parent, and a sickle hemoglobin gene (Hb S) from the other parent. This results in hemoglobin AS or sickle cell trait. A person with sickle cell trait may also be called a sickle cell carrier. Sickle cell trait is not a disease and usually does not affect one's health, but individuals with sickle cell trait can pass the sickle hemoglobin gene to their children.