The conditions for which your baby will be tested are individually rare. However, they are also very serious and can result in severe injury to the brain, organs, or nervous system, and/or may result in death if not treated. The newborn blood spot screen helps to identify the babies needing treatment, such as a special diet or medication. Since symptoms are not generally noticeable at birth, the best way to find these disorders before permanent damage occurs is through newborn screening. Only additional testing (diagnostic testing) can tell if the baby truly has the disorder. The screening tests are very good but not fail-safe and may not always detect a disorder. In any case, if your baby does not seem well, talk to your baby's doctor as soon as possible.